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Cerebral palsy

Spastic paralysis; Paralysis - spastic; Spastic hemiplegia; Spastic diplegia; Spastic quadriplegia

Cerebral palsy is a group of disorders that can involve brain, which affects nervous system functions, such as movement, learning, hearing, seeing, and thinking.

There are several different types of cerebral palsy, including spastic, dyskinetic, ataxic, hypotonic, and mixed.

Causes

Cerebral palsy is caused by injuries or abnormalities of the brain. Most of these problems occur as the baby grows in the womb. But they can happen at any time during the first 2 years of life, while the baby's brain is still developing.

In some people with cerebral palsy, parts of the brain are injured due to a low level of oxygen (hypoxia) in those areas. It is not known why this occurs.

Premature infants have a slightly higher risk of developing cerebral palsy. Cerebral palsy may also occur during early infancy as a result of several conditions, including:

  • Bleeding in the brain
  • Brain infections (encephalitis, meningitis, herpes simplex infections)
  • Head injury
  • Infections in the mother during pregnancy (rubella)
  • Untreated jaundice
  • Injuries to brain during the childbirth process

In some cases, the cause of cerebral palsy is never determined.

Symptoms

Symptoms of cerebral palsy can be very different between people with this group of disorders. Symptoms may:

  • Be very mild or very severe
  • Only involve one side of the body or both sides
  • Be more pronounced in either the arms or legs, or involve both the arms and legs

Symptoms are usually seen before a child is 2 years old. Sometimes symptoms begin as early as 3 months. Parents may notice that their child is delayed in reaching developmental stages such as sitting, rolling, crawling, or walking.

There are several different types of cerebral palsy. Some people have a mix of symptoms.

Spastic cerebral palsy is the most common type. Symptoms include:

  • Muscles that are very tight and do not stretch. They may tighten even more over time.
  • Abnormal walk (gait) -- arms tucked in toward the sides, knees crossed or touching, legs make "scissors" movements, walk on the toes.
  • Joints are tight and do not open all the way (called joint contracture).
  • Muscle weakness or loss of movement in a group of muscles (paralysis).
  • Symptoms may affect one arm or leg, one side of the body, both legs, or both arms and legs.

The following symptoms may occur in other types of cerebral palsy:

  • Abnormal movements (twisting, jerking, or writhing) of the hands, feet, arms, or legs while awake, which gets worse during periods of stress
  • Tremors
  • Unsteady gait
  • Loss of coordination
  • Floppy muscles, especially at rest, and joints that move around too much

Other brain and nervous system symptoms may include:

  • Learning disabilities are common, but intelligence can be normal
  • Speech problems (dysarthria)
  • Hearing or vision problems
  • Seizures
  • Pain, especially in adults, which can be difficult to manage

Eating and digestion symptoms:

  • Difficulty sucking or feeding in infants, or chewing and swallowing in older children and adults
  • Vomiting or constipation

Other symptoms:

  • Increased drooling
  • Slower than normal growth
  • Irregular breathing
  • Urinary incontinence

Exams and Tests

The health care provider will perform a full neurologic exam. In older people, testing cognitive function is also important.

Other tests may be performed as needed, most often to rule out other disorders:

Treatment

There is no cure for cerebral palsy. The goal of treatment is to help the person be as independent as possible.

Treatment requires a team approach, including:

  • Primary care doctor
  • Dentist (dental check-ups are recommended around every 6 months)
  • Social worker
  • Nurses
  • Occupational, physical, and speech therapists
  • Other specialists, including a neurologist, rehabilitation physician, pulmonologist, and gastroenterologist

Treatment is based on the person's symptoms and the need to prevent complications.

Self and home care include:

  • Getting enough food and nutrition
  • Keeping the home safe
  • Performing exercises recommended by the providers
  • Practicing proper bowel care (stool softeners, fluids, fiber, laxatives, regular bowel habits)
  • Protecting the joints from injury

Putting the child in regular schools is recommended unless physical disabilities or mental development makes this impossible. Special education or schooling may help.

The following may help with communication and learning:

  • Glasses
  • Hearing aids
  • Muscle and bone braces
  • Walking aids
  • Wheelchairs

Physical therapy, occupational therapy, orthopedic help, or other treatments may also be needed to help with daily activities and care.

Medicines may include:

  • Anticonvulsants to prevent or reduce the frequency of seizures
  • Botulinum toxin to help with spasticity and drooling
  • Muscle relaxants to reduce tremors and spasticity

Surgery may be needed in some cases to:

  • Control gastroesophageal reflux
  • Cut certain nerves from the spinal cord to help with pain and spasticity
  • Place feeding tubes
  • Release joint contractures

Support Groups

Stress and burnout among parents and other caregivers of people with cerebral palsy is common. Seek support and more information from organizations that specialize in cerebral palsy.

Outlook (Prognosis)

Cerebral palsy is a life-long disorder. Long-term care may be required. The disorder does not affect expected length of life. The amount of disability varies.

Many adults are able to live in the community, either independently or with different levels of help.

Possible Complications

Cerebral palsy may lead to the following health problems:

  • Bone thinning (osteoporosis)
  • Bowel obstruction
  • Hip dislocation and arthritis in the hip joint
  • Injuries from falls
  • Pressure sores
  • Joint contractures
  • Pneumonia caused by choking
  • Poor nutrition
  • Reduced communication skills (sometimes)
  • Reduced intellect (sometimes)
  • Scoliosis
  • Seizures (in about half of the people who are affected by cerebral palsy)
  • Social stigma

When to Contact a Medical Professional

Call your provider if symptoms of cerebral palsy develop, especially if you know that an injury occurred during birth or early infancy.

Prevention

Getting the proper prenatal care may reduce the risk for some rare causes of cerebral palsy. In most cases though, the injury causing the disorder is not preventable.

Pregnant mothers with certain medical conditions may need to be followed in a high-risk prenatal clinic.

References

Greenberg JM, Haberman B, Narendran V, Nathan AT, Schibler K. Neonatal morbidities of prenatal and perinatal origin. In: Resnik R, Lockwood CJ, Moore TR, Greene MF, Copel JA, Silver RM, eds. Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice. 8th ed. Philadelphia, PA: Elsevier; 2019:chap 73.

Johnston MV. Encephalopathies. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 616.

Nass R, Sidhu R, Ross G. Autism and other developmental disabilities. In: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology in Clinical Practice. 7th ed. Philadelphia, PA: Elsevier; 2016:chap 90.

Oskoui M, Shevell MI, Swaiman KF. Cerebral palsy. In: Swaiman KF, Ashwal S, Ferriero DM, et al, eds. Swaiman's Pediatric Neurology: Principles and Practice. 6th ed. Philadelphia, PA: Elsevier; 2017:chap 97.

Verschuren O, Peterson MD, Balemans AC, Hurvitz EA. Exercise and physical activity recommendations for people with cerebral palsy. Dev Med Child Neurol. 2016;58(8):798-808. PMID: 26853808 www.ncbi.nlm.nih.gov/pubmed/26853808.

    • Cerebral palsy

      Animation

    •  

      Cerebral palsy - Animation

      The words cerebral palsy or (CP) may conjure up an image of a twisted, wheel chair-bound child. But sometimes the disease is so mild it doesn't limit any activity at all. Let's talk about cerebral palsy. So, what causes cerebral palsy? CP is caused by injuries or abnormalities of the brain. Most of the problems occur as the baby grows in the womb. Premature babies have a slightly higher risk of developing CP. Cerebral palsy may also occur during early infancy as a result of several conditions, including Bleeding in the brain, Brain infections, Head injuries, infections in the mother during pregnancy or from severe jaundice. CP can affect one limb, one side of the body, both arms or legs, three limbs, or all four limbs. The limbs might be floppy, rigid, or spastic. They might have a tremor, move on their own, or be uncoordinated. The limbs might function so well most people would not notice, or they might even be unusable. Children with CP might have normal or superior intellect. Up to a quarter of children with CP have developmental delays or mental retardation. Your child's doctor will do a full neurological exam of your child to verify the symptoms. Tests might include a CT scan or MRI of the head, an EEG, and vision and hearing tests. There is no cure for CP. The goal of treatment is to help your child be as independent as possible. Your child may need a team consisting of a primary care doctor, dentist, social worker, nurses, specialists, and occupational, physical, and speech therapists. A variety of medicines can prevent or reduce the frequency of seizures, help with spasticity, and treat tremors. CP is a lifelong disorder. But with good care it shouldn't get worse over time. CP varies in each individual...your child may need lifelong care, or your child may be able to live independently. It all depends on the severity of your child's CP. Keep in mind that stress and burnout among parents of children with severe CP is common, so make sure that you get the support you need, as well as the support for your child.

    • Central nervous system and peripheral nervous system

      Central nervous system and peripheral nervous system - illustration

      The central nervous system comprises the brain and spinal cord. The peripheral nervous system includes all peripheral nerves.

      Central nervous system and peripheral nervous system

      illustration

    • Cerebral palsy

      Animation

    •  

      Cerebral palsy - Animation

      The words cerebral palsy or (CP) may conjure up an image of a twisted, wheel chair-bound child. But sometimes the disease is so mild it doesn't limit any activity at all. Let's talk about cerebral palsy. So, what causes cerebral palsy? CP is caused by injuries or abnormalities of the brain. Most of the problems occur as the baby grows in the womb. Premature babies have a slightly higher risk of developing CP. Cerebral palsy may also occur during early infancy as a result of several conditions, including Bleeding in the brain, Brain infections, Head injuries, infections in the mother during pregnancy or from severe jaundice. CP can affect one limb, one side of the body, both arms or legs, three limbs, or all four limbs. The limbs might be floppy, rigid, or spastic. They might have a tremor, move on their own, or be uncoordinated. The limbs might function so well most people would not notice, or they might even be unusable. Children with CP might have normal or superior intellect. Up to a quarter of children with CP have developmental delays or mental retardation. Your child's doctor will do a full neurological exam of your child to verify the symptoms. Tests might include a CT scan or MRI of the head, an EEG, and vision and hearing tests. There is no cure for CP. The goal of treatment is to help your child be as independent as possible. Your child may need a team consisting of a primary care doctor, dentist, social worker, nurses, specialists, and occupational, physical, and speech therapists. A variety of medicines can prevent or reduce the frequency of seizures, help with spasticity, and treat tremors. CP is a lifelong disorder. But with good care it shouldn't get worse over time. CP varies in each individual...your child may need lifelong care, or your child may be able to live independently. It all depends on the severity of your child's CP. Keep in mind that stress and burnout among parents of children with severe CP is common, so make sure that you get the support you need, as well as the support for your child.

    • Central nervous system and peripheral nervous system

      Central nervous system and peripheral nervous system - illustration

      The central nervous system comprises the brain and spinal cord. The peripheral nervous system includes all peripheral nerves.

      Central nervous system and peripheral nervous system

      illustration

    Review Date: 6/23/2019

    Reviewed By: Alireza Minagar, MD, MBA, Professor, Department of Neurology, LSU Health Sciences Center, Shreveport, LA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

    The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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