Multiple myelomaPlasma cell dyscrasia; Plasma cell myeloma; Malignant plasmacytoma; Plasmacytoma of bone; Myeloma - multiple
Multiple myeloma is a blood cancer that starts in the plasma cells in the bone marrow. Bone marrow is the soft, spongy tissue found inside most bones. It helps make blood cells.
Plasma cells help your body fight infection by producing proteins called antibodies. With multiple myeloma, plasma cells grow out of control in the bone marrow and form tumors in the areas of solid bone. The growth of these bone tumors weakens the solid bones. It also makes it harder for the bone marrow to make healthy blood cells and platelets.
National Cancer Institute website. PDQ plasma cell neoplasms (including multiple myeloma) treatment. www.cancer.gov/types/myeloma/hp/myeloma-treatment-pdq. Updated July 19, 2019. Accessed February 13, 2020.
National Comprehensive Cancer Network website. NCCN clinical practice guidelines in oncology: multiple myeloma. Version 2.2020. www.nccn.org/professionals/physician_gls/pdf/myeloma.pdf. Updated October 9, 2019. Accessed February 13, 2020.
Rajkumar SV, Dispenzieri A. Multiple myeloma and related disorders. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff’s Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 101.